Pathogens reWritE Rho's Rules

نویسندگان

  • Richard D. Hayward
  • Vassilis Koronakis
چکیده

Many bacterial pathogens use a specialized "type III" secretion system to deliver virulence effector proteins into host mammalian cells. In this issue of Cell, Alto et al. (2006) describe a new family of effectors that share a WxxxE sequence motif. These effectors directly stimulate host signaling pathways by mimicking activated Ras-like cellular GTPases.

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عنوان ژورنال:
  • Cell

دوره 124  شماره 

صفحات  -

تاریخ انتشار 2006